Blood group isoantibody stimulation in man by feeding blood group-active bacteria

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Blood group isoantibody stimulation in man by feeding blood group-active bacteria.

It was investigated whether or not the human blood group isoantibodies A and B could be induced by immunogenic stimuli via natural routes with a kind of antigenic substance to which all humans are commonly exposed, or if the appearance of these antibodies is independent of antigenic stimuli as has long been believed. Escherichia coli O(86), which possess high human blood group B and faint A act...

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Distribution of blood group A, B, and H(O) activities among 282 aerobic Gram-negative bacteria, many isolated from the blood of patients, has been studied. Almost half of these bacteria were found to be blood group active. About 10 per cent of the organisms exhibited high, disproportional activities, which in some instances approached those of crude human blood group mucoids. No significant, sp...

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ژورنال

عنوان ژورنال: Journal of Clinical Investigation

سال: 1969

ISSN: 0021-9738

DOI: 10.1172/jci106094